5-HTP ( 5-Hydroxytryptophan) is a supplement that is known to increase satiety and should be taken with food. 5-HTP appears to reliably reduce food intake to around 60% of baseline values (placebo groups tend to hit 80%).
5-HTP should not be used alongside anti-depressant medication, in particular SSRIs or MAOIs.
Alpha Lipoic Acid is very reliable for reducing appetite in research animals via suppressing hypothalamic AMPK (a mechanism similar to the hormone leptin). The beginning bit of human research tends to agree with the large body of animal research.
There is a possibility that it is not effective in humans, so this one remains preliminary.
For the creation of this content, I have used Examine.com as a main source of data-driven information.